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Published in ACS Chemical Neuroscience
Merc M Kemeh, Anthony J Furnelli, Noel Lazo
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Highly Toxic Aβ Begets More Aβ
Published in Neural Regeneration Research
Merc M. Kemeh, Noel D. Lazo
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Merc M. Kemeh, Noel D. Lazo
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Modulation of the Activity of the Insulin-degrading Enzyme by Aβ Peptides
Published in ACS Chemical Neuroscience
Merc M. Kemeh, Noel D. Lazo
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Exchange Broadening Underlies the Enhancement of IDE-Dependent Degradation of Insulin by Anionic Membranes
2022
2022
Vol. 7
Issue #28
Qiuchen Zheng, Bethany Lee, Micheal T. Kebede, Valerie A. Ivancic, Merc M. Kemeh, Henrique Lemos Brito, Donald E. Spratt, Noel D. Lazo
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Differential Effects of Polyphenols on Insulin Proteolysis by the Insulin-Degrading Enzyme
Published in Antioxidants (Basel)
2021
2021
Vol. 10
Issue #9
Qiuchen Zheng, Micheal T. Kebede, Bethany Lee, Claire A. Krasinski, Saadman Islam, Liliana A. Wurfl, Merc M. Kemeh, Valerie A. Ivancic, Charles E. Jakobsche, Donald E. Spratt, Noel D. Lazo
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Helix Dipole and Membrane Electrostatics Delineate Conformational Transitions in the Self-Assembly of Amyloidogenic Peptides
2020
2020
Vol. 36
Issue #29
Qiuchen Zheng, Senegal N. Carty, Noel D. Lazo
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Inhibition of the Self-Assembly of Aβ and of Tau by Polyphenols: Mechanistic Studies
2019
2019
Vol. 24
Issue #12
Qiuchen Zheng, Micheal T. Kebede, Merc M. Kemeh, Saadman Islam, Bethany Lee, Stuart D. Bleck, Liliana A. Wurfl, Noel D. Lazo
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Resveratrol Sustains Insulin-Degrading Enzyme Activity toward Aβ42
2018
2018
Vol. 3
Issue #10
Claire A. Krasinski, Valerie A. Ivancic, Qiuchen Zheng, Donald E. Spratt, Noel D. Lazo
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Enzyme kinetics from circular dichroism of insulin reveals mechanistic insights into the regulation of insulin-degrading enzyme
2018
2018
Vol. 38
Issue #6
Valerie A. Ivancic, Claire A. Krasinski, Qiuchen Zheng, Rebecca J. Meservier, Donald E. Spratt, Noel D. Lazo
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The Longest Amyloid-β Precursor Protein Intracellular Domain Produced with Aβ42 Forms β-Sheet-Containing Monomers That Self-Assemble and Are Proteolyzed by Insulin-Degrading Enzyme
Published in ACS Chem Neurosci
2018
2018
Vol. 9
Issue #12
Claire A. Krasinski, Qiuchen Zheng, Valerie A. Ivancic, Donald E. Spratt, Noel D. Lazo
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Mechanistic Studies of the Inhibition of Insulin Fibril Formation by Rosmarinic Acid
Published in J Phys Chem B
2018
2018
Vol. 122
Issue #8
Qiuchen Zheng, Noel D. Lazo
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A versatile platform for adding functional properties to amyloid fibrils
Published in Org Biomol Chem
2017
2017
Vol. 15
Issue #38
Devon Fontaine, Valerie A. Ivancic, Michael B. Reardon, Noel D. Lazo, Charles E. Jakobsche
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Binding Modes of Thioflavin T on the Surface of Amyloid Fibrils Studied by NMR
Published in Chemphyschem
2016
2016
Vol. 17
Issue #16
Valerie A. Ivancic, Oshini Ekanayake, Noel D. Lazo
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K114 (trans, trans)-bromo-2,5-bis(4-hydroxystyryl)benzene is an efficient detector of cationic amyloid fibrils
2015
2015
Vol. 24
Issue #3
Veli Selmani, Kevin J. Robbins, Valerie A. Ivancic, Noel D. Lazo
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Conformational analysis of thioflavin T bound to the surface of amyloid fibrils
2012
2012
Vol. 28
Issue #48
Kevin J. Robbins, Gai Liu, Veli Selmani, Noel D. Lazo
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Kinetic profile of amyloid formation in the presence of an aromatic inhibitor by nuclear magnetic resonance
Published in ACS Med Chem Lett
2012
2012
Vol. 3
Issue #10
Gai Liu, Jennifer C. Gaines, Kevin J. Robbins, Noel D. Lazo
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Curcumin modulates the self-assembly of the islet amyloid polypeptide by disassembling α-helix
Published in Biochem Biophys Res Commun
2012
2012
Vol. 422
Issue #4
Samuel Sparks, Gai Liu, Kevin J. Robbins, Noel D. Lazo
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Helix-dipole effects in peptide self-assembly to amyloid
Published in Biochemistry
2012
2012
Vol. 51
Issue #20
Gai Liu, Kevin J. Robbins, Samuel Sparks, Veli Selmani, Kalin M. Bilides, Erin E. Gomes, Noel D. Lazo
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Mechanistic studies of peptide self-assembly: transient α-helices to stable β-sheets
Published in J Am Chem Soc
2010
2010
Vol. 132
Issue #51
Gai Liu, Anabathula Prabhakar, Darryl Aucoin, Miranda Simon, Samuel Sparks, Kevin J. Robbins, Andrew Sheen, Sarah A. Petty, Noel D. Lazo