Noel Lazo

Scholarly and Creative Works

• Other Scholarly or Creative Work

  How Aβ peptides modulate insulin degradation in Alzheimer's and diabetes

  ●

  2024

  Merc Kemeh

  ,

  Noel Lazo

• Article in Refereed Journal

  Highly Toxic Aβ Begets More Aβ

  Published in Neural Regeneration Research

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  2024

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  Vol. 19

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  Issue #9

  Merc Kemeh

  ,

  Noel Lazo

• Article in Refereed Journal

  Modulation of the Activity of the Insulin-degrading Enzyme by Aβ Peptides

  Published in ACS Chemical Neuroscience

  ●

  2023

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  Vol. 14

  Merc Kemeh

  ,

  Noel Lazo

• Article in Refereed Journal

  Exchange Broadening Underlies the Enhancement of IDE-Dependent Degradation of Insulin by Anionic Membranes

  Published in ACS Omega

  2022

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  2022

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  Vol. 7

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  Issue #28

  Qiuchen Zheng

  ,

  Bethany Lee

  ,

  Micheal Kebede

  ,

  Valerie Ivancic

  ,

  Merc Kemeh

  ,

  Henrique Brito

  ,

  Donald Spratt

  ,

  Noel Lazo

• Article in Refereed Journal

  Differential Effects of Polyphenols on Insulin Proteolysis by the Insulin-Degrading Enzyme

  Published in Antioxidants (Basel)

  2021

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  2021

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  Vol. 10

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  Issue #9

  Qiuchen Zheng

  ,

  Micheal Kebede

  ,

  Bethany Lee

  ,

  Claire Krasinski

  ,

  Saadman Islam

  ,

  Liliana Wurfl

  ,

  Merc Kemeh

  ,

  Valerie Ivancic

  ,

  Charles Jakobsche

  ,

  Donald Spratt

  ,

  Noel Lazo

• Article in Refereed Journal

  Helix Dipole and Membrane Electrostatics Delineate Conformational Transitions in the Self-Assembly of Amyloidogenic Peptides

  Published in Langmuir

  2020

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  2020

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  Vol. 36

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  Issue #29

  Qiuchen Zheng

  ,

  Senegal Carty

  ,

  Noel Lazo

• Article in Refereed Journal

  Inhibition of the Self-Assembly of Aβ and of Tau by Polyphenols: Mechanistic Studies

  Published in Molecules

  2019

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  2019

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  Vol. 24

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  Issue #12

  Qiuchen Zheng

  ,

  Micheal Kebede

  ,

  Merc Kemeh

  ,

  Saadman Islam

  ,

  Bethany Lee

  ,

  Stuart Bleck

  ,

  Liliana Wurfl

  ,

  Noel Lazo

• Article in Refereed Journal

  Mechanistic Studies of the Inhibition of Insulin Fibril Formation by Rosmarinic Acid

  Published in J Phys Chem B

  2018

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  2018

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  Vol. 122

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  Issue #8

  Qiuchen Zheng

  ,

  Noel Lazo

• Article in Refereed Journal

  The Longest Amyloid-β Precursor Protein Intracellular Domain Produced with Aβ42 Forms β-Sheet-Containing Monomers That Self-Assemble and Are Proteolyzed by Insulin-Degrading Enzyme

  Published in ACS Chem Neurosci

  2018

  ●

  2018

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  Vol. 9

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  Issue #12

  Claire Krasinski

  ,

  Qiuchen Zheng

  ,

  Valerie Ivancic

  ,

  Donald Spratt

  ,

  Noel Lazo

• Article in Refereed Journal

  Enzyme kinetics from circular dichroism of insulin reveals mechanistic insights into the regulation of insulin-degrading enzyme

  Published in Biosci Rep

  2018

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  2018

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  Vol. 38

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  Issue #6

  Valerie Ivancic

  ,

  Claire Krasinski

  ,

  Qiuchen Zheng

  ,

  Rebecca Meservier

  ,

  Donald Spratt

  ,

  Noel Lazo

• Article in Refereed Journal

  Resveratrol Sustains Insulin-Degrading Enzyme Activity toward Aβ42

  Published in ACS Omega

  2018

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  2018

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  Vol. 3

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  Issue #10

  Claire Krasinski

  ,

  Valerie Ivancic

  ,

  Qiuchen Zheng

  ,

  Donald Spratt

  ,

  Noel Lazo

• Article in Refereed Journal

  A versatile platform for adding functional properties to amyloid fibrils

  Published in Org Biomol Chem

  2017

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  2017

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  Vol. 15

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  Issue #38

  Devon Fontaine

  ,

  Valerie Ivancic

  ,

  Michael Reardon

  ,

  Noel Lazo

  ,

  Charles Jakobsche

• Article in Refereed Journal

  Binding Modes of Thioflavin T on the Surface of Amyloid Fibrils Studied by NMR

  Published in Chemphyschem

  2016

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  2016

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  Vol. 17

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  Issue #16

  Valerie Ivancic

  ,

  Oshini Ekanayake

  ,

  Noel Lazo

• Article in Refereed Journal

  K114 (trans, trans)-bromo-2,5-bis(4-hydroxystyryl)benzene is an efficient detector of cationic amyloid fibrils

  Published in Protein Sci

  2015

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  2015

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  Vol. 24

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  Issue #3

  Veli Selmani

  ,

  Kevin Robbins

  ,

  Valerie Ivancic

  ,

  Noel Lazo

• Article in Refereed Journal

  Helix-dipole effects in peptide self-assembly to amyloid

  Published in Biochemistry

  2012

  ●

  2012

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  Vol. 51

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  Issue #20

  Gai Liu

  ,

  Kevin Robbins

  ,

  Samuel Sparks

  ,

  Veli Selmani

  ,

  Kalin Bilides

  ,

  Erin Gomes

  ,

  Noel Lazo

• Article in Refereed Journal

  Curcumin modulates the self-assembly of the islet amyloid polypeptide by disassembling α-helix

  Published in Biochem Biophys Res Commun

  2012

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  2012

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  Vol. 422

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  Issue #4

  Samuel Sparks

  ,

  Gai Liu

  ,

  Kevin Robbins

  ,

  Noel Lazo

• Article in Refereed Journal

  Kinetic profile of amyloid formation in the presence of an aromatic inhibitor by nuclear magnetic resonance

  Published in ACS Med Chem Lett

  2012

  ●

  2012

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  Vol. 3

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  Issue #10

  Gai Liu

  ,

  Jennifer Gaines

  ,

  Kevin Robbins

  ,

  Noel Lazo

• Article in Refereed Journal

  Conformational analysis of thioflavin T bound to the surface of amyloid fibrils

  Published in Langmuir

  2012

  ●

  2012

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  Vol. 28

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  Issue #48

  Kevin Robbins

  ,

  Gai Liu

  ,

  Veli Selmani

  ,

  Noel Lazo

• Article in Refereed Journal

  Mechanistic studies of peptide self-assembly: transient α-helices to stable β-sheets

  Published in J Am Chem Soc

  2010

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  2010

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  Vol. 132

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  Issue #51

  Gai Liu

  ,

  Anabathula Prabhakar

  ,

  Darryl Aucoin

  ,

  Miranda Simon

  ,

  Samuel Sparks

  ,

  Kevin Robbins

  ,

  Andrew Sheen

  ,

  Sarah Petty

  ,

  Noel Lazo