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Jacqueline M. Dresch, Luke L. Nourie, Regan D. Conrad, Lindsay T. Carlson, Elizabeth I. Tchantouridze, Biruck Tessema, Eleanor Verhagen, Mahima Gupta, Diego Borges-Rivera, Robert A. Drewell
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Experimental approaches to investigate biophysical interactions between homeodomain transcription factors and DNA
Published in Biochimica et biophysica acta. Gene regulatory mechanisms
Fadwa Mekkaoui, Robert A Drewell, Jacqueline M Dresch, Donald E Spratt
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Published in BMC Genomics
2024
2024
Vol. 25
Issue #1
Robert A. Drewell, Daniel Klonaros, Jacqueline M. Dresch
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The Dictyostelium discoideum genome lacks significant DNA methylation and uncovers palindromic sequences as a source of false positives in bisulfite sequencing
Published in NAR Genomics and Bioinformatics
Robert Drewell, Tayla C Cormier, Jacob L Steenwyk, James St. Denis, Javier F Tabima Restrepo, Jacqueline M. Dresch, Denis A Larochelle
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Published in G3: Genes|Genomes|Genetics
Daniel Klonaros, Jacqueline M. Dresch, Robert Drewell
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Jacqueline M. Dresch, Regan D. Conrad, Daniel Klonaros, Robert Drewell
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Improving bioinformatic tools using protein-DNA binding data
Joint Mathematics Meetings
Hynes Convention Center, Boston, MA
Jacqueline M. Dresch
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Transcriptome profile in Drosophila Kc and S2 embryonic cell lines
Published in G3 Genes|Genomes|Genetics
Daniel Klonaros, Jacqueline M Dresch, Robert A Drewell
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Published in Mathematical Biosciences
Michael Gaiewski, Robert Drewell, Jacqueline M. Dresch
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Biophysical and structural analysis of Antennapedia and Ultrabithorax homeodomain transcription factor-DNA binding affinities
Protein Science
Jeanmarie Loss, Jacqueline M. Dresch, Robert Drewell, Donald E. Spratt
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Analyzing the stability of gene expression using a simple reaction-diffusion model in an early Drosophila embryo
Published in Mathematical biosciences
Gregory D McCarthy, Robert A Drewell, Jacqueline M Dresch
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Rapid and efficient purification of Drosophila homeodomain transcription factors for biophysical characterization
Published in Protein expression and purification
Rachel Orlomoski, Aaron Bogle, Jeanmarie Loss, Rylee Simons, Jacqueline M Dresch, Robert A Drewell, Donald E Spratt
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Getting the most out of an interdisciplinary undergraduate research experience
Gryphon and Pleiades Honors Society Seminar Series
Clark University
Sponsored by Gryphon and Pleiades Honors Society
Jacqueline M. Dresch
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Biophysical and structural analysis of Drosophila transcription factors
Next-in-BIO 2018
Worcester MA
Aaron Bogle, Jacqueline M. Dresch, Robert Drewell, Donald E. Spratt
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The folded k-spectrum kernel: A machine learning approach to detecting transcription factor binding sites with gapped nucleotide dependencies
Abdulkadir Elmas, Xiaodong Wang, Jacqueline M Dresch
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Whole genome bisulfite sequencing reveals a sparse, but robust pattern of DNA methylation in the Dictyostelium discoideum genome
Jacob Steenwyk, James St. Denis, Jacqueline M. Dresch, Denis A Larochelle, Robert Drewell
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Spatial distribution of predicted transcription factor binding sites in Drosophila ChIP peaks
Published in Mechanisms of development
Kade P Pettie, Jacqueline M Dresch, Robert A Drewell
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Quantitative perturbation-based analysis of gene expression predicts enhancer activity in early Drosophila embryo
Rupinder Sayal, Jacqueline M Dresch, Irina Pushel, Benjamin R Taylor, David N Arnosti
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Nucleotide Interdependency in Transcription Factor Binding Sites in the Drosophila Genome
Published in Gene regulation and systems biology
Jacqueline M Dresch, Rowan G Zellers, Daniel K Bork, Robert A Drewell
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The Wisdom of Crowds: Can Mathematical Models Crack the cis Regulatory Code?
Published in Cell systems
Jacqueline M Dresch, David N Arnosti
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Global sensitivity analysis of a dynamic model for gene expression in Drosophila embryos
Gregory D McCarthy, Robert A Drewell, Jacqueline M Dresch
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MARZ: an algorithm to combinatorially analyze gapped n-mer models of transcription factor binding
Published in BMC bioinformatics
Rowan G Zellers, Robert A Drewell, Jacqueline M Dresch
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Deciphering the combinatorial architecture of a Drosophila homeotic gene enhancer
Published in Mechanisms of development
Robert A Drewell, Michael J Nevarez, Je S Kurata, Laure N Winkler, Lily Li, Jacqueline M Dresch
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A primer on thermodynamic-based models for deciphering transcriptional regulatory logic
Published in Biochimica et biophysica acta
Jacqueline M Dresch, Megan Richards, Ahmet Ay
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Flanking sequence context-dependent transcription factor binding in early Drosophila development
Published in BMC bioinformatics
Jessica L Stringham, Adam S Brown, Robert A Drewell, Jacqueline M Dresch
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TWO-LAYER MATHEMATICAL MODELING OF GENE EXPRESSION: INCORPORATING DNA-LEVEL INFORMATION AND SYSTEM DYNAMICS
Published in SIAM journal on applied mathematics
Jacqueline M Dresch, M A Thompson, David N Arnosti, Chichia Chiu
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Global parameter estimation for thermodynamic models of transcriptional regulation
Published in Methods (San Diego, Calif.)
Yerzhan Suleimenov, Ahmet Ay, Md A Samee, Jacqueline M Dresch, Saurabh Sinha, David N Arnosti
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Thermodynamic modeling of transcription: sensitivity analysis differentiates biological mechanism from mathematical model-induced effects
Published in BMC systems biology
Jacqueline M Dresch, Xiaozhou Liu, David N Arnosti, Ahmet Ay
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Network structure, and vaccination strategy and effort interact to affect the dynamics of influenza epidemics
Published in Journal of theoretical biology
G Hartvigsen, J M Dresch, A L Zielinski, A J Macula, C C C Leary
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Biophysical DNA binding activities of the EVEN-SKIPPED and FUSHI-TARAZU homeodomain transcription factors
Published in Plos Genetics
Jacqueline M. Dresch, Fadwa Mekkaoui, Don E. Spratt, Robert Drewell
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Identification of novel components of the retinal determination gene network in Drosophila cell lines
Published in Open Biology
Robert Drewell, Jacqueline M. Dresch
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Dissecting the function of the DNMT2-homolog (DNMA) in Dictyostelium discoideum
Zaza Gelasvili, Denis A Larochelle, Jacqueline M. Dresch, Maddie Hincher, Javier F Tabima Restrepo, Robert Drewell