Risk Modeling with a Focus on Cellular Repair Mechanisms
for Radiation-Induced Damage
Principal Investigator: Robert
radiation holds a special place among environmental carcinogens
because of the extent of information available about radiation
effects on humans, on other animals, and on cells and cell systems.
The information available has been enhanced recently with the
availability of new genetic assays that shed light on both low
dose effects and the rates of processes, such as DNA repair, that
can modify the expected incidence of effects at low doses and
dose rates. With so much information available along with very
substantial ongoing research efforts, now is a propitious time
to attempt syntheses in the form of biologically based risk models.